# Publications & Preprints Search Within Results Search Within Results search ## 18 results Show filters filter\_alt Sort by Year of PublicationAlphabetical A-Z sort ## 18 results Download 18 citations download- [BibTeX](/node/1659446/export?format=bibtex) - [EndNote X3 XML](/node/1659446/export?format=endnote8) - [EndNote 7 XML](/node/1659446/export?format=endnote7) - [Endnote tagged](/node/1659446/export?format=tagged) - [Marc](/node/1659446/export?format=marc) - [PubMedId](/node/1659446/export?format=pubmed_id) - [RIS](/node/1659446/export?format=ris) ### 2022 Tri Nguyen, Logan Thomas, Jeff Rhoades, Ilaria Ricchi, Xintong Cindy Yuan, Arlo Sheridan, David Hildebrand, Jan Funke, Wade Regehr, and Wei-Chung Allen Lee. 2022. “[Structured Cerebellar Connectivity Supports Resilient Pattern Separation](/publications/structured-cerebellar-connectivity-supports-resilient-pattern-separation)”. Nature. doi:10.1038/s41586-022-05471-w Tri Nguyen, Logan Thomas, Jeff Rhoades, Ilaria Ricchi, Xintong Cindy Yuan, Arlo Sheridan, David Hildebrand, Jan Funke, Wade Regehr, and Wei-Chung Allen Lee. 2022. “[Structured Cerebellar Connectivity Supports Resilient Pattern Separation](/publications/structured-cerebellar-connectivity-supports-resilient-pattern-separation)”. Nature. doi:10.1038/s41586-022-05471-w - add\_circle do\_not\_disturb\_on Abstract The cerebellum is thought to help detect and correct errors between intended and executed commands1,2 and is critical for social behaviours, cognition and emotion3-6. Computations for motor control must be performed quickly to correct errors in real time... Tomas Osorno, Stephanie Rudolph, Tri Nguyen, Velina Kozareva, Naeem Nadaf, Aliya Norton, Evan Macosko, Wei-Chung Allen Lee, and Wade Regehr. 2022. “[Candelabrum Cells Are Ubiquitous Cerebellar Cortex Interneurons With Specialized Circuit Properties](/publications/candelabrum-cells-are-ubiquitous-cerebellar-cortex-interneurons)”. Nat Neurosci, 25, 6, Pp. 702-13. doi:10.1038/s41593-022-01057-x Tomas Osorno, Stephanie Rudolph, Tri Nguyen, Velina Kozareva, Naeem Nadaf, Aliya Norton, Evan Macosko, Wei-Chung Allen Lee, and Wade Regehr. 2022. “[Candelabrum Cells Are Ubiquitous Cerebellar Cortex Interneurons With Specialized Circuit Properties](/publications/candelabrum-cells-are-ubiquitous-cerebellar-cortex-interneurons)”. Nat Neurosci, 25, 6, Pp. 702-13. doi:10.1038/s41593-022-01057-x - add\_circle do\_not\_disturb\_on Abstract To understand how the cerebellar cortex transforms mossy fiber (MF) inputs into Purkinje cell (PC) outputs, it is vital to delineate the elements of this circuit. Candelabrum cells (CCs) are enigmatic interneurons of the cerebellar cortex that have been... Yajun Xie, Aaron Kuan, Wengang Wang, Zachary Herbert, Olivia Mosto, Olubusola Olukoya, Manal Adam, Steve Vu, Minsu Kim, Diana Tran, Nicolás Gómez, Claire Charpentier, Ingie Sorour, Tiara Lacey, Michael Tolstorukov, Bernardo Sabatini, Wei-Chung Allen Lee, and Corey Harwell. 2022. “[Astrocyte-Neuron Crosstalk through Hedgehog Signaling Mediates Cortical Synapse Development](/publications/astrocyte-neuron-crosstalk-through-hedgehog-signaling-mediates-cortical-0)”. Cell Rep, 38, 8, Pp. 110416. doi:10.1016/j.celrep.2022.110416 Yajun Xie, Aaron Kuan, Wengang Wang, Zachary Herbert, Olivia Mosto, Olubusola Olukoya, Manal Adam, Steve Vu, Minsu Kim, Diana Tran, Nicolás Gómez, Claire Charpentier, Ingie Sorour, Tiara Lacey, Michael Tolstorukov, Bernardo Sabatini, Wei-Chung Allen Lee, and Corey Harwell. 2022. “[Astrocyte-Neuron Crosstalk through Hedgehog Signaling Mediates Cortical Synapse Development](/publications/astrocyte-neuron-crosstalk-through-hedgehog-signaling-mediates-cortical-0)”. Cell Rep, 38, 8, Pp. 110416. doi:10.1016/j.celrep.2022.110416 - add\_circle do\_not\_disturb\_on Abstract Neuron-glia interactions play a critical role in the regulation of synapse formation and circuit assembly. Here we demonstrate that canonical Sonic hedgehog (Shh) pathway signaling in cortical astrocytes acts to coordinate layer-specific synaptic... Jenny Lu, Amir Behbahani, Lydia Hamburg, Elena Westeinde, Paul Dawson, Cheng Lyu, Gaby Maimon, Michael Dickinson, Shaul Druckmann, and Rachel Wilson. 2022. “[Transforming Representations of Movement from Body- to World-Centric Space](/publications/transforming-representations-movement-body-world-centric-space-0)”. Nature, 601, 7891, Pp. 98-104. doi:10.1038/s41586-021-04191-x Jenny Lu, Amir Behbahani, Lydia Hamburg, Elena Westeinde, Paul Dawson, Cheng Lyu, Gaby Maimon, Michael Dickinson, Shaul Druckmann, and Rachel Wilson. 2022. “[Transforming Representations of Movement from Body- to World-Centric Space](/publications/transforming-representations-movement-body-world-centric-space-0)”. Nature, 601, 7891, Pp. 98-104. doi:10.1038/s41586-021-04191-x - add\_circle do\_not\_disturb\_on Abstract When an animal moves through the world, its brain receives a stream of information about the body's translational velocity from motor commands and sensory feedback signals. These incoming signals are referenced to the body, but ultimately, they must be... Aaron Kuan, Giulio Bondanelli, Laura Driscoll, Julie Han, Minsu Kim, David Hildebrand, Brett Graham, Logan Thomas, Stefano Panzeri, Christopher Harvey, and Wei-Chung Allen Lee. 2022. “[Synaptic Wiring Motifs in Posterior Parietal Cortex Support Decision-Making](https://doi.org/10.1101/2022.04.13.488176)”. BioRxiv Aaron Kuan, Giulio Bondanelli, Laura Driscoll, Julie Han, Minsu Kim, David Hildebrand, Brett Graham, Logan Thomas, Stefano Panzeri, Christopher Harvey, and Wei-Chung Allen Lee. 2022. “[Synaptic Wiring Motifs in Posterior Parietal Cortex Support Decision-Making](https://doi.org/10.1101/2022.04.13.488176)”. BioRxiv - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2022.04.13.488176v1) The posterior parietal cortex (PPC) exhibits choice-selective activity during perceptual decision-making tasks. However, it is not known how this selective activity arises from the underlying synaptic connectivity. Here, we combined virtual reality... - [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2022.04.13.488176v1) Akira Mamiya, Pralaksha Gurung, Igor Siwanowicz, Anne Sustar, Chenghao Chen, Jasper Phelps, Aaron Kuan, Alexandra Pacureanu, Wei-Chung Allen Lee, Natasha Mhatre, and John C. Tuthill. 2022. “[Biomechanical Origins of Proprioceptive Maps in the Drosophila Leg](https://doi.org/10.1101/2022.08.08.503192)”. BioRxiv Akira Mamiya, Pralaksha Gurung, Igor Siwanowicz, Anne Sustar, Chenghao Chen, Jasper Phelps, Aaron Kuan, Alexandra Pacureanu, Wei-Chung Allen Lee, Natasha Mhatre, and John C. Tuthill. 2022. “[Biomechanical Origins of Proprioceptive Maps in the Drosophila Leg](https://doi.org/10.1101/2022.08.08.503192)”. BioRxiv - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2022.08.08.503192v1) Proprioception, the sense of body position and movement, is essential for effective motor control. Because proprioceptive sensory neurons are embedded in complex and dynamic tissues, it has been challenging to understand how they sense and encode... - [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2022.08.08.503192v1) ### 2021 Chenghao Chen, Sweta Agrawal, Brandon Mark, Akira Mamiya, Anne Sustar, Jasper Phelps, Wei-Chung Allen Lee, Barry Dickson, Gwyneth Card, and John Tuthill. 2021. “[Functional Architecture of Neural Circuits for Leg Proprioception in Drosophila](/publications/functional-architecture-neural-circuits-leg-proprioception-drosophila)”. Curr Biol, 31, 23, Pp. 5163-5175.e7. doi:10.1016/j.cub.2021.09.035 Chenghao Chen, Sweta Agrawal, Brandon Mark, Akira Mamiya, Anne Sustar, Jasper Phelps, Wei-Chung Allen Lee, Barry Dickson, Gwyneth Card, and John Tuthill. 2021. “[Functional Architecture of Neural Circuits for Leg Proprioception in Drosophila](/publications/functional-architecture-neural-circuits-leg-proprioception-drosophila)”. Curr Biol, 31, 23, Pp. 5163-5175.e7. doi:10.1016/j.cub.2021.09.035 - add\_circle do\_not\_disturb\_on Abstract To effectively control their bodies, animals rely on feedback from proprioceptive mechanosensory neurons. In the Drosophila leg, different proprioceptor subtypes monitor joint position, movement direction, and vibration. Here, we investigate how these... Julia Buhmann, Arlo Sheridan, Stephan Gerhard, Renate Krause, Tri Nguyen, Larissa Heinrich, Philipp Schlegel, Wei-Chung Allen Lee, Rachel Wilson, Stephan Saalfeld, Gregory Jeffferis, Davi Bock, Srinivas Turaga, Matthew Cook, and Jan Funke. 2021. “[Automatic Detection of Synaptic Partners in a Whole-Brain Drosophila EM Dataset.](/publications/automatic-detection-synaptic-partners-whole-brain-drosophila-em-dataset)”. Nature Methods, 18, Pp. 711-74 Julia Buhmann, Arlo Sheridan, Stephan Gerhard, Renate Krause, Tri Nguyen, Larissa Heinrich, Philipp Schlegel, Wei-Chung Allen Lee, Rachel Wilson, Stephan Saalfeld, Gregory Jeffferis, Davi Bock, Srinivas Turaga, Matthew Cook, and Jan Funke. 2021. “[Automatic Detection of Synaptic Partners in a Whole-Brain Drosophila EM Dataset.](/publications/automatic-detection-synaptic-partners-whole-brain-drosophila-em-dataset)”. Nature Methods, 18, Pp. 711-74 - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.nature.com/articles/s41592-021-01183-7) The study of neural circuits requires the reconstruction of neurons and the identification of synaptic connections between them. To scale the reconstruction to the size of whole-brain datasets, semi-automatic methods are needed to solve those tasks. Here... - [ descriptionPublisher's Version](https://www.nature.com/articles/s41592-021-01183-7) Sarah J. Pfau, Urs H. Langen, Theodore M. Fisher, Indumathi Prakash, Faheem Nagpurwala, Ricardo A. Lozoya, Wei-Chung Allen Lee, Zhuhao Wu, and Chenghua Gu. 2021. “[Vascular and Perivascular Cell Profiling Reveals the Molecular and Cellular Bases of Blood-Brain Barrier Heterogeneity](https://doi.org/10.1101/2021.04.26.441465)”. BioRxiv Sarah J. Pfau, Urs H. Langen, Theodore M. Fisher, Indumathi Prakash, Faheem Nagpurwala, Ricardo A. Lozoya, Wei-Chung Allen Lee, Zhuhao Wu, and Chenghua Gu. 2021. “[Vascular and Perivascular Cell Profiling Reveals the Molecular and Cellular Bases of Blood-Brain Barrier Heterogeneity](https://doi.org/10.1101/2021.04.26.441465)”. BioRxiv - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2021.04.26.441465v1) The blood-brain barrier (BBB) is critical for protecting the brain and maintaining neuronal homeostasis. Although the BBB is a unique feature of the central nervous system (CNS) vasculature, not all brain regions have the same degree of impermeability... - [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2021.04.26.441465v1) Arlo Sheridan, Tri Nguyen, Diptodip Deb, Wei-Chung Allen Lee, Stephan Saalfeld, Srinivas Turaga, Uri Manor, and Jan Funke. 2021. “[Local Shape Descriptors for Neuron Segmentation](https://doi.org/10.1101/2021.01.18.427039)”. BioRxiv Arlo Sheridan, Tri Nguyen, Diptodip Deb, Wei-Chung Allen Lee, Stephan Saalfeld, Srinivas Turaga, Uri Manor, and Jan Funke. 2021. “[Local Shape Descriptors for Neuron Segmentation](https://doi.org/10.1101/2021.01.18.427039)”. BioRxiv - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2021.01.18.427039v1) We present a simple, yet effective, auxiliary learning task for the problem of neuron segmentation in electron microscopy volumes. The auxiliary task consists of the prediction of Local Shape Descriptors (LSDs), which we combine with conventional voxel... - [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2021.01.18.427039v1) Jasper S. Phelps, David Grant Colburn Hildebrand, Brett J. Graham, Aaron T. Kuan, Logan A. Thomas, Tri Nguyen, Julia Buhmann, Anthony W. Azevedo, Anne Sustar, Sweta Agrawal, Mingguan Liu, Brendan L. Shanny, Jan Funke, John C. Tuthill, and Wei-Chung Allen Lee. 2021. “[Reconstruction of Motor Control Circuits in Adult Drosophila Using Automated Transmission Electron Microscopy](https://doi.org/10.1016/j.cell.2020.12.013)”. Cell, 184, 3, Pp. 759–774 Jasper S. Phelps, David Grant Colburn Hildebrand, Brett J. Graham, Aaron T. Kuan, Logan A. Thomas, Tri Nguyen, Julia Buhmann, Anthony W. Azevedo, Anne Sustar, Sweta Agrawal, Mingguan Liu, Brendan L. Shanny, Jan Funke, John C. Tuthill, and Wei-Chung Allen Lee. 2021. “[Reconstruction of Motor Control Circuits in Adult Drosophila Using Automated Transmission Electron Microscopy](https://doi.org/10.1016/j.cell.2020.12.013)”. Cell, 184, 3, Pp. 759–774 - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.cell.com/cell/fulltext/S0092-8674(20)31683-4) To investigate circuit mechanisms underlying locomotor behavior, we used serial-section electron microscopy (EM) to acquire a synapse-resolution dataset containing the ventral nerve cord (VNC) of an adult female Drosophila melanogaster. To generate this... - [ descriptionPublisher's Version](https://www.cell.com/cell/fulltext/S0092-8674(20)31683-4) ### 2020 Aaron Kuan, Jasper Phelps, Logan Thomas, Tri M. Nguyen, Julie Han, Chiao-Lin Chen, Anthony Azevedo, John Tuthill, Jan Funke, Peter Cloetens, Alexandra Pacureanu, and Wei-Chung Allen Lee. 2020. “[Dense Neuronal Reconstruction through X-Ray Holographic Nano-Tomography](https://doi.org/10.1038/s41593-020-0704-9)”. Nat Neurosci, 23, 12, Pp. 1637–1643 Aaron Kuan, Jasper Phelps, Logan Thomas, Tri M. Nguyen, Julie Han, Chiao-Lin Chen, Anthony Azevedo, John Tuthill, Jan Funke, Peter Cloetens, Alexandra Pacureanu, and Wei-Chung Allen Lee. 2020. “[Dense Neuronal Reconstruction through X-Ray Holographic Nano-Tomography](https://doi.org/10.1038/s41593-020-0704-9)”. Nat Neurosci, 23, 12, Pp. 1637–1643 - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.nature.com/articles/s41593-020-0704-9) Imaging neuronal networks provides a foundation for understanding the nervous system, but resolving dense nanometer-scale structures over large volumes remains challenging for light microscopy (LM) and electron microscopy (EM). Here we show that X-ray... - [ descriptionPublisher's Version](https://www.nature.com/articles/s41593-020-0704-9) - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [ Next page chevron\_right ](?page=1 "Go to next page")